PERCEIVED CAUSAL NETWORKS: CLINICAL UTILITY EVALUATED BY THERAPISTS AND PATIENTS


Elder (Sambucus nigra), identified by high-content screening, counteracts foam cell formation without promoting hepatic lipogenesis

Abstract Cholesterol deposition in intimal macrophages leads to foam here cell formation and atherosclerosis.Reverse cholesterol transport (RCT), initiated by efflux of excess cholesterol from foam cells, counteracts atherosclerosis.However, targeting RCT by enhancing cholesterol efflux was so far accompanied by adverse hepatic lipogenesis.Here, we

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